THE ANTIOXIDANT AND ANTI-HEPATIC FIBROSIS ACTIVITIES OF ACORNS (QUERCUS LIAOTUNGENSIS) AND THEIR NATURAL GALLOYL TRITERPENES

The antioxidant and anti-hepatic fibrosis activities of acorns (Quercus liaotungensis) and their natural galloyl triterpenes

Acorn is an edible plant and it has also been used as traditional food.In our investigation of the antioxidant and anti-hepatic fibrosis constituents of acorns (Quercus liaotungensis), the novel galloyl triterpenes were discovered, their potential mechanisms were investigated by Rods microscope observation, and western blot.Evaluation of their anti

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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion

Summary: PSGL-1 (P-selectin glycoprotein-1) is a T cell-intrinsic checkpoint regulator of exhaustion with an unknown mechanism of action.Here, Li-Ion/Li-Po Chargers we show that PSGL-1 acts upstream of PD-1 and requires co-ligation with the T cell receptor (TCR) to attenuate activation of mouse and human CD8+ T cells and drive terminal T cell exhau

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High Diversity and Novel Enteric Viruses in Fecal Viromes of Healthy Wild and Captive Thai Cynomolgus Macaques (Macaca fascicularis)

Cynomolgus macaques are common across South East Asian countries including Thailand.The National Primate Research Center of Thailand, Chulalongkorn University (NPRCT-CU) captures wild-borne cynomolgus macaque for research use.Limited information is available on the enteric viruses and possible zoonotic infections into or from cynomolgus macaques.We

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